Rates and Predictors of Conversion to Schizophrenia or Bipolar Disorder Following Substance-Induced Psychosis

Cannabis-induced psychosis (CIP) has the highest conversion rate to schizophrenia of any substance-induced psychosis (ie opioids, amphetamines). A large register-based cohort study from Denmark found over 40% of patients who experienced CIP were diagnosed with schizophrenia within the 20 year study period, half converted within 3 years. Patients aged 16-25 had the highest risk for conversion to schizophrenia.

Cannabis-induced psychosis (CIP) has the highest conversion rate to schizophrenia of any substance-induced psychosis (ie opioids, amphetamines). A large register-based cohort study from Denmark found over 40% of patients who experienced CIP were diagnosed with schizophrenia within the 20 year study period, half converted within 3 years. Patients aged 16-25 had the highest risk for conversion to schizophrenia.

By Marie Stefanie Kejser Starzer, M.D.; Merete Nordentoft, Dr.Med.Sc.; Carsten Hjorthøj, Ph.D., M.Sc.

 

Read the full study at The American Journal of Psychiatry.